Name | Stachyose tetrahydrate |
Synonyms | 6)- manneotetrose STACHOSE TETRAHYDRATE Stachyose tetrahydrate 6)-alpha-D-glucopyranoside STACHYOSE FROM STACHYS TUBERIFERA*HYDRAT E α-d-gal-(1→6)-α-d-gal-(1→6)-α-d-glc-(1→2)-β-d-fru alpha-d-galactosyl-alpha-d-galactosyl-alpha-d-glucosyl-beta-d-fructose beta-d-fructofuranosyl-o-alpha-d-galactopyranosyl-(1-6)-o-alpha-d-galactopyranosyl-(1-6)-alpha-d-glucopyranoside |
CAS | 10094-58-3 |
EINECS | 207-427-3 |
InChI | InChI=1/C24H42O21.4H2O/c25-1-6-10(28)14(32)17(35)21(41-6)39-3-8-11(29)15(33)18(36)22(42-8)40-4-9-12(30)16(34)19(37)23(43-9)45-24(5-27)20(38)13(31)7(2-26)44-24;;;;/h6-23,25-38H,1-5H2;4*1H2/t6-,7-,8-,9-,10+,11+,12-,13-,14+,15+,16+,17-,18-,19-,20+,21+,22+,23-,24+;;;;/m1..../s1 |
Molecular Formula | C24H50O25 |
Molar Mass | 738.64 |
Melting Point | 95-105 °C |
Boling Point | 1044.2°C at 760 mmHg |
Specific Rotation(α) | [α]24/D +133°, c = 4 in H2O |
Flash Point | 585.3°C |
Solubility | Soluble in water, insoluble in organic solvents such as ether and ethanol |
Vapor Presure | 0mmHg at 25°C |
Appearance | White crystalline powder |
Color | White to Off-White |
Storage Condition | Sealed in dry,Room Temperature |
Stability | Hygroscopic |
Refractive Index | 133 ° (C=5, H2O) |
MDL | MFCD00149457 |
In vitro study | Stachyose tetrahydrate inhibits Caco-2 cell proliferation and induces apoptosis in a dose-dependent manner. Stachyose highly promotes proliferation of lactic acid bacteria (LAB) by inducing LAB to produce more α-galactosidase to hydrolyze stachyose. |
Safety Description | 24/25 - Avoid contact with skin and eyes. |
WGK Germany | 3 |
FLUKA BRAND F CODES | 10 |
HS Code | 29400090 |
Reference Show more | 1. Yu Jing, Zeng Xiaoqun, Pan Daodong, et al. Processing Technology of Highly Active Probiotic Yogurt Containing Stachyose [J]. Chinese Journal of Food 2017 17(003):105-112. 2. Wang Donghui, Liao Na, Sun Peng, Ji Xueqi, Li Xianen, Qin Minjian. Changes of Sugar Content in Different Organs of Rehmannia glutinosa [J]. Chinese Journal of Traditional Chinese Medicine, 2018,43(08):1563-1570. 3. Fang Xiao, Duan Rongshuai, Wang Fengshan. Effect of Oligosaccharides on Biological Activity of Lactobacillus [J]. Pharmaceutical Biotechnology 2014 21(04):338-342. 4. Tian Lei, Li Enyuan, Guan Tongwei, Tang Shukun, Liu Xiaofei, Zhang Xiaoping. Diversity, Functional Enzyme and Antibacterial Activity Screening of Cultured Halophilic Bacteria in Ading Lake [J]. Microbiology Bulletin, 2017,44(11):2575-2587. 5. Song Linlin, Xue Shujuan, Wang Lili, Zhang Fei, Chen Suiqing. Chemical Composition Analysis of Rehmannia glutinosa with Different Storage Years [J]. Chinese patent medicine, 2020,42(10):2661-2669. 6. Zhang, s., Li, j., Xie, c., Wu, q., Yu, j., & Tang, k. (2021). Resolution enhancement of overlapping peaks of ion mobility spectrometry based on improved particle swarm optimization algorithm. Rapid Communications in Mass Spectrometry, 35(1), e8935. 7. Li, Hongbo, et al. "Development of a microencapsulated synbiotic product and its application in yoghurt." LWT 122 (2020): 109033.https://doi.org/10.1016/j.lwt. 2020.109033 8. [IF=9.954] Li-Fang Zhu et al."A core-shell multi-drug platform to improve gastrointestinal tract microbial health using 3D printing."Biofabrication. 2020 Mar;12(2):025026 9. [IF=6.057] Chengyi Xie et al."Improving glycan isomeric separation via metal ion incorporation for drift tube ion mobility-mass spectrometry."Talanta. 2020 May;211:120719 10. [IF=6.057] Yuting Li et al."Methylation in combination with temperature programming enables rapid identification of polysaccharides by ambient micro-fabrication glow discharge plasma (MFGDP) desorption ionization mass spectrometry."Talanta. 2020 Oct;218:121156 11. [IF=4.952] Yin Zheng et al."Characterization of fermented soymilk by Schleiferilactobacillus harbinensis M1, based on the whole-genome sequence and corresponding phenotypes."Lwt Food Sci Technol. 2021 Jun;144:111237 12. [IF=3.935] Biru Shi et al."Investigation on the stability in plant metabolomics with a special focus on freeze-thaw cycles: LC-MS and NMR analysis to Cassiae Semen (Cassia obtusifolia L.) seeds as a case study."J Pharmaceut Biomed. 2021 Sep;204:114243 13. [IF=2.104] Jianhua Xie et al."A thermophilic fungal GH36 α-galactosidase from Lichtheimia ramosa and its synergistic hydrolysis of locust bean gum."Carbohyd Res. 2020 May;491:107911 14. [IF=6.558] Yuanqing Luo et al."Pd nanoparticles decorated thiol-functionalized MOF as an efficient matrix for differentiation and quantitation of oligosaccharide isomers by laser desorption/ionization mass spectrometry."Anal Chim Acta. 2022 Apr;1202:339665 |
overview | the pure stachyose is a white powder, which is a kind of four sugars existing in nature, with light sweetness and pure taste. Its molecular structure: "galactose-galactose-glucose-fructose", the molecular formula is C24H42O21. Stachyose has obvious proliferation effect on bifidobacteria, lactobacillus and other beneficial flora in human gastrointestinal tract, which can rapidly improve the environment in human digestive tract and regulate the balance of microecological flora. Promote the formation of beneficial bacteria in the digestive tract The dominant bacteria status, inhibit the production of spoilage bacteria such as Clostridium aerogenes, in addition to the production of a large number of physiologically active substances, regulate the pH of the intestine, kill pathogenic bacteria, inhibit the production of spoilage products, inhibit the production and absorption of endogenous agents, and decompose and derive multiple immune functional factors. Commonly known as: food with beneficial bacteria. |
Introduction | Stachyose is a tetrasaccharide composed of fructose-glucose-galactose-galactose. The molecular formula is C24H42O21. It is a refractory sugar. After being ingested, it can be directly connected to the E. coli for use by beneficial bacteria such as Bifidobacterium, inhibit the rise of cholesterol, comprehensively improve the intestinal environment, and improve the absorption of trace elements such as calcium and magnesium. |
biological activity | Stachyose tetrahydrate, a functional oligosaccharide, can be used as prebiotics. Stachyose tetrahydrate can indirectly prevent the growth of colon cancer cells by promoting the proliferation of probiotics or producing beneficial substances in the intestine. |
use | mannooligosaccharides are helpful for the proliferation of beneficial bacteria in intestinal tract, and can be selectively fermented and utilized by beneficial bacteria in digestive tract flora. at the same time, the acidic substances produced will reduce the PH value of the whole intestinal tract and inhibit the growth of harmful bacteria. Therefore, mannan oligosaccharides are called "pathogen adsorbent" or "pathogen scavenger" |